New Secondary Metabolites of Mangrove-Associated Strains

Year: 2024

Type: article

Abstract: Positioned at the dynamic interface between terrestrial and marine realms, mangroves embody a vibrant tapestry of biodiversity, encompassing an array of plants, animals, and microorganisms. These microbial inhabitants of mangrove habitats have emerged as a pivotal resource for antimicrobials and a plethora of pharmaceutically valuable compounds, spanning enzymes, antineoplastic agents, pesticides, immunosuppressants, and immunomodulators. This review delves into the recent landscape (January 2021 to May 2024, according to the time of publication) of novel secondary metabolites isolated from mangrove-associated microorganisms, analyzing 41 microbial strains that collectively yielded 165 distinct compounds. Our objective is to assess the productivity and potential of natural products derived from microbial populations within mangrove ecosystems in recent times. Notably, fungi stand out as the preeminent contributors to the emergence of these novel natural products, underscoring their pivotal role in the bioprospecting endeavors within these unique environments.

Source: Marine Drugs

DOI: 10.3390/md22080372

Authors: Yunxia Yu, Zimin Wang, Dingmi Xiong, Liman Zhou, Fandong Kong, Qi Wang

Institutions: Guangxi Minzu University, State Ethnic Affairs Commission, Hainan Maternal and Child Health Hospital

Language: English

Topic: Microbial Natural Products and Biosynthesis

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

Open Access status: gold

Estimated APC paid: $3,296

Funders: National Natural Science Foundation of China, Natural Science Foundation of Guangxi Province, Natural Science Foundation of Hainan Province, Specific Research Project of Guangxi for Research Bases and Talents

OpenAlex ID: W4401634844