Work

Synthesis of 2-Azetidinones via Cycloaddition Approaches: An Update

Year: 2024

Type: article

Abstract: The present review is a comprehensive update of the synthesis of monocyclic β-lactams via cycloaddition reactions. According to the IUPAC definition of cycloaddition, both elementary and stepwise processes (formal cycloadditions) have been considered. The years 2019-2022 are covered by the cited literature. The focus of the review is on synthetic aspects with emphasis on the structural scope, reaction conditions, mechanistic aspects, and selectivity results. Selected significant data related to biological activities and synthetic applications are also highlighted.

Source: Reactions

DOI: 10.3390/reactions5030026

Authors: Franca Maria Cordero, Donatella Giomi, Fabrizio Machetti

Institutions: University of Florence, Institute for the Chemistry of OrganoMetallic Compounds, National Research Council

Language: English

Topic: Synthesis of β-Lactam Compounds

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,137

OpenAlex ID: W4401637379

FWCI: 1.389

Cites: 189

Cited by: 10

Related to: 10