Work

Digital Ulceration Following Gemcitabin Plus Cisplatin Chemotherapy in a Systemic Sclerosis Patient With Lung Adenocarcinoma

Year: 2024

Type: article

Abstract: Systemic sclerosis (SSc) is a systemic autoimmune disease characterized by fibrosis and vascular dysfunction in the skin and visceral organ systems. Digital ulceration is one of the major cause of morbidity. Although its pathogenesis has not been fully elucidated, structural and functional disturbances in small vessels are considered one of the major mechanisms. While cold exposure is considered the most important inciting factor for the development of digital ulceration, drugs and physical trauma are other described triggering factors. Herein, we report a case with SSc diagnosis who developed digital ulcers following gemcitabine and cisplatin chemotherapy for lung adenocarcinoma.

Source: Rheumatology Quarterly

DOI: 10.4274/qrheumatol.galenos.2024.08108

Authors: Hüseyin Oruç, Reşit Yıldırım, Nazife Şule Yaşar Bilge, Timuçin Kaşifoğlu

Institution: Eskişehir Osmangazi University

Language: English

Topic: Systemic Sclerosis and Related Diseases

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4401639902