Wilhelm Keller MD (1818–1877) and the emergence of xenobiochemistry
Year: 2024
Type: article
Abstract: Although there had been many previous inklings, the field of xenobiotic metabolism (as we know it today) began with an experiment reported in the 1841 literature proclaiming that the ingestion of benzoic acid led to the subsequent excretion of hippuric acid in human urine. A metabolic transformation undertaken by a living organism. One worker involved in the early stages of this discovery was Wilhelm Keller, although very little information about him is readily available. Hopefully, this article will go some way to counter this dearth and also highlight Keller's pioneering contribution in the development of the fields of drug metabolism and xenobiochemistry.
Source: Journal of Medical Biography
Authors: Stephen Mitchell, Rosemary Waring
Institutions: Imperial College London, University of Birmingham
Language: English
Subfield: History and Philosophy of Science
Field: Arts and Humanities
Domain: Social Sciences
Open Access status: hybrid
Estimated APC paid: $3,950
OpenAlex ID: W4401640325