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Effects of Transverse Abdominis Plane (TAP) Block on the MACBAR of Sevoflurane in Gynecologic Patients with Laparoscopic Pneumoperitoneal Stimulation: An Up-Down Sequential Allocation Study

Year: 2024

Type: article

Abstract: Purpose: This study aimed to observe the effect of bilateral transverse abdominis plane (TAP) block on the MAC BAR of sevoflurane in gynecological patients with laparoscopic pneumoperitoneal stimulation. Patients and Methods: Fifty patients who underwent laparoscopic surgery were randomly assigned to either the control group ( n = 25) or the TAP block group ( n = 25). Patients in the TAP block group were subjected to a bilateral transversal abdominal muscle plane block with 0.33% ropivacaine (20 mL on each side) guided by ultrasound. The control group received an equal volume of normal saline. The MAC BAR of sevoflurane in each group was determined using a sequential allocation technique. Results: The MAC BAR of sevoflurane in the TAP block group was significantly lower than that in the control group (4.20% [95% confidence interval {CI}, 4.02%– 4.38%] vs 5.03% [95% CI, 4.89%– 5.18%]). Conclusion: Bilateral TAP block can reduce the MAC BAR of sevoflurane in gynecological patients with pneumoperitoneum stimulation. Trial Registration Number: ChiCTR2100046517. The trial is publicly available and registered at www.chictr.org.cn on May 18, 2021. Keywords: Transverse abdominis plane block, Adrenergic response, Minimum alveolar concentration, Pneumoperitoneum stimulation, Sevoflurane

Source: Journal of Pain Research

DOI: 10.2147/jpr.s469342

Authors: PingPing Jiang, JingTao Tang, Min Zhang, Dan Wang

Institutions: Affiliated Hospital of North Sichuan Medical College, North Sichuan Medical University

Language: English

Topic: Anesthesia and Pain Management

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,836