Work

Case report: Thoracic vertebral abscess caused by Salmonella via diagnosed next-generation sequencing

Year: 2024

Type: article

Abstract: The genus Salmonella consists of Gram-negative bacteria with various serotypes. It commonly causes bacterial infections that affect the intestines. Infection can occur in humans and animals through the ingestion of contaminated food or water, or through contact with infected animals or environments. Complications commonly include intestinal hemorrhage and perforation, though vertebral osteomyelitis is rarely observed. Therefore, in patients with spinal cord abscesses, The genus Salmonella is typically not considered a likely pathogen, especially in the absence of typical symptoms. In this case, the limited information provided by traditional cultivation methods, particularly under the influence of antibiotics. However, next-generation sequencing (NGS) unexpectedly detected Salmonella, which assisted in formulating the final treatment plan. This underscores the role and clinical value of NGS in pathogen identification.

Source: Frontiers in Medicine

DOI: 10.3389/fmed.2024.1419356

Authors: Xiao-guang Cao, Jun-xi Ni, Chong-jian Huang

Institutions: University of Science and Technology of China, Anhui Provincial Hospital, Third People's Hospital of Hefei, Anhui Medical University, Suzhou Municipal Hospital

Language: English

Topic: Infectious Diseases and Tuberculosis

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,295