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A Wax Interface‐Enabled One‐Pot Multiplexed Nucleic Acid Testing Platform for Rapid and Sensitive Detection of Viruses and Variants (Small Methods 8/2024)

Year: 2024

Type: article

Abstract: Virus Detection In article number 2400030, Cheng, Xu, and co-workers propose a one-tube diagnostic method based on a wax interface, achieving a rapid and highly sensitive detection of viruses and their variants. The waterfall under sunlight symbolizes melted wax interface by heating and then DNA amplification products of RT-RPA drop. Concurrently, the boats represent the CRISPR/Cas12a, where the illuminated light indicates the emitting probe when successfully catching target DNA.

Source: Small Methods

DOI: 10.1002/smtd.202470047

Authors: Jiajia Liu, Nan Li, Li Zhang, Ying Lu, Minjie Shen, Yuanyue Zhang, Li Feng, Juhui Jing, Jing Cheng, Youchun Xu

Institutions: Capital Medical University, Tsinghua University, Chinese Academy of Sciences, State Key Laboratory of Transducer Technology, Aerospace Information Research Institute

Language: English

Topic: Biosensors and Analytical Detection

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: bronze

OpenAlex ID: W4401668776

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