Work

8-Iodo-4-methyl-2-oxo-2H-chromen-7-yl Benzenesulfonate

Year: 2024

Type: article

Abstract: We report a straightforward and efficient synthesis of 4-methyl-2-oxo-2H-chromen-7-yl benzenesulfonate (3a) and 8-iodo-4-methyl-2-oxo-2H-chromen-7-yl benzenesulfonate (3b) in good yields through an O-sulfonylation reaction of 7-hydroxy-2H-chromen-2-ones 1a and 1b with benzenesulfonyl chloride 2 mediated by triethylamine in dichloromethane at ambient temperature. The aryl sulfonyl esters were characterized using spectroscopic, spectrometric, and thermal analyses.

Source: Molbank

DOI: 10.3390/m1869

Authors: Luis Pulido-Moreno, Andrés Parra-Tibocha, Alexander Ladino-Bejarano, Mario A. Macías, Diana Becerra, Juan-Carlos Castillo

Institutions: Pedagogical and Technological University of Colombia, Universidad de Los Andes

Language: English

Topic: Synthesis of Organic Compounds

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

Open Access status: gold

Estimated APC paid: $568

OpenAlex ID: W4401697945

FWCI:

Cites: 15

Cited by:

Related to: 10