Work

Chimerism and mosaicism shape our physical constitution and impact medical conditions

Year: 2024

Type: article

Abstract: ABO blood group discrepancies in healthy individuals were caused by body-wide chimerism and mosaicism. They can be evaluated with new diagnostic options for disease-related cell clones that are typically associated with mosaicism. The observations raise the attention for sporadic mixed-field observations of any blood group antigen. Commentary on: Dauber et al. Body-wide chimerism and mosaicism are predominant causes of naturally occurring ABO discrepancies. Br J Haematol 2024; 205:1188-1196.

Source: British Journal of Haematology

DOI: 10.1111/bjh.19705

Author: Willy Albert Flegel

Institutions: National Institutes of Health, Georgetown University Medical Center, National Institutes of Health Clinical Center

Language: English

Topic: Blood groups and transfusion

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,940