Work

Flexible intracortical probes for stable neural recording: from the perspective of structure

Year: 2024

Type: article

Abstract: Electrical neural interfaces provide direct communication pathways between living brain tissue and engineered devices to understand brain function. However, conventional neural probes have remained limited in providing stable, long-lasting recordings because of large mechanical and structural mismatches with respect to brain tissue. The development of flexible probes provides a promising approach to tackle these challenges. In this review, various structural designs of flexible intracortical probes for promoting long-term neural integration, including thin film filament and mesh probe structures that provide similar geometric and mechanical properties to brain tissue and self-deployable probe structure that enables moving the functional sensors away from the insertion trauma, are summarized, highlighting the important role of structural design in improving the long-term recording stability of neural probes.

Source: Flexible and Printed Electronics

DOI: 10.1088/2058-8585/ad71dc

Authors: Suhao Wang, Qianqian Jiang, Jizhou Song

Institution: Zhejiang University

Language: English

Topic: Neuroscience and Neural Engineering

Subfield: Cellular and Molecular Neuroscience

Field: Neuroscience

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $3,165

Funders: National Natural Science Foundation of China, Fundamental Research Funds for the Central Universities