Smart Microneedle Arrays Integrating Cell‐Free Therapy and Nanocatalysis to Treat Liver Fibrosis (Adv. Sci. 31/2024)
Year: 2024
Type: article
Abstract: Smart Microneedle Arrays for Liver Fibrosis Treatment In article number 2309940, Kai Li, Yu Tao, Mingqiang Li, and co-workers present a versatile microneedle array integrating cell-free therapy and nanocatalysis for liver fibrosis treatment. These microneedles release core-shell nanoparticles encapsulating stem cell secretome, which deactivate hepatic stellate cells, rejuvenate hepatocytes, and suppress inflammation. Additionally, the released nanozymes scavenge reactive oxygen species and alleviate hypoxia. This innovative therapeutic strategy demonstrates remarkable efficacy in treating liver fibrosis.
Source: Advanced Science
Authors: Yanteng Xu, Yixin Zhang, Hao Tian, Qingguo Zhong, Ke Yi, Fenfang Li, Tiantian Xue, Haixia Wang, Yeh‐Hsing Lao, Yingying Xu, Yinxiong Li, Ling Long, Kai Li, Yu Tao, Mingqiang Li
Language: English
Subfield: Hepatology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $6,120
OpenAlex ID: W4401722304