Year: 2024
Type: article
Study design: Case Report
Abstract: Hepatoblastoma is a rare type of pediatric malignant disease and represents the most frequent cause of liver tumors during childhood. We describe the diagnosis and treatment of a 14-month-old female patient who presented with abdominal swelling, anorexia, and weight loss. Initial investigations indicated elevated alpha-fetoprotein levels and thrombocytosis. A CT scan showed a heterogeneous mass arising in the right lobe of the liver. Histology revealed hepatoblastoma, epithelial type, and fetal pattern. The patient was treated as a standard risk according to the Pretext classification (Pretext I-III) with neoadjuvant Cisplatin (4 cycles) following the SIOPEL 3 protocol, resulting in a 40% reduction in tumor size and a successful partial hepatectomy.
Language: English
Subfield: Hepatology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4401724750