Work

Impact of segregation and integration on infection dynamics: analysis of a Cholera model in a two-population system

Year: 2024
Type: article
Abstract: We present a novel dynamic model designed to depict Cholera outbreaks within a two-population framework featuring two environmental reservoirs. The model is designed to emulate the impact of segregation or integration between two populations on the transmission of the disease and infections throughout the entire community, both with and without non-medicinal interventions. This is achieved by allowing infectious individuals to interact with the reservoir of the alternate population at different levels of suppression, in addition to their regular interaction with their own reservoir. We find out that increased suppression of cross community interaction reduces the number of infections in the overall population as well as in the population with less contamination and contact. Additionally, we predict significant delays in the occurrence of peak infections, affording public health authorities crucial time for intervention. Lowering cross-immunity interactions also leads to a decrease in bacterial concentrations in environmental reservoirs. Finally, we demonstrate that non-medicinal interventions, including sanitation and water purification, would significantly reduce and delay infections, providing a valuable time frame for implementing additional medicinal measures.
Language: English
Field: Medicine
Open Access status: hybrid
Estimated APC paid: $2,285
OpenAlex ID: W4401732254
FWCI: 0.754
Cites: 44
Cited by: 2
Related to: 10