Work

Hematological, inflammatory and serological responses among COVID-19 patients admitted to intensive care unit

Year: 2024

Type: article

Abstract: Aim: To correlate hematological, inflammatory indicators and serological responses among COVID-19 patients to point out the significant biomarkers for disease management and prognosis.Materials & methods: Standard analytical and molecular methods were used to assess various inflammatory and serological Responses among COVID-19 patients (ICU- (n = 99) and non-ICU patients (n = 64) as compared with health control (n = 40).Results: Significant differences in the Hb, WBC, Lymphocyte count, CRP and serum ferritin (p < 0.05) were observed. Patients' IgM/IgG antibodies against SARS-CoV-2 were associated with increased CRP, LDH and serum ferritin levels.Conclusion: A significant association between serum IgG/IgM and ICU admission was observed. Although serum ferritin and LDH can offer information about the extent of inflammation, they are exclusive factors for ICU admission.

Source: Future Science OA

DOI: 10.1080/20565623.2024.2389664

Authors: Mirette A Morgan, Sarra E Saleh, Azza H Salamoni, Mohammad Y Alshahrani, Khaled M Aboshanab

Institutions: Ministry of Health and Population, Ain Shams University, Egypt Center for Research and Regenerative Medicine, King Khalid University

Language: English

Topic: COVID-19 Clinical Research Studies

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,165