Waste-derived Ca and Zn-based bimetallic (Ca/Zn) nanorods encapsulated chitosan-based haemostatic dressing bandage: A step towards waste to bandages
Year: 2024
Type: article
Abstract: Controlling loss of blood during militant war, traumatic injury , and surgical procedures is the greatest challenge nowadays, which leads to death, thereby the necessity of hemostatic bandages. The present work focuses on the synthesis of waste-derived (WD)-Ca incorporated Zn nanorods encapsulated with chitosan polymers (CZC) to control the loss of blood as well as bacterial infection. The as-prepared CZC bandage was tested against various biochemical tests such as PBS absorption, hemolysis, adsorption of protein , platelets aggregation/adhesion, blood clotting ability, and antibacterial test assay. The data suggested that the CZC bandage has high biocompatibility , exceptional PBS absorption ability (∼1402%), platelets aggregation (∼65%) within 10 min of exposure, protein a loading ability (∼37 mg/cm 2 ), and ∼84% blood clotting within a 1 min of exposure. Moreover, the CZC bandage effectively kills/inhibits both E. Coli and S. aureus bacteria. Therefore, the prepared CZC bandage in this study is simple, economically viable, and sustainable development.
Authors: Pooja Thakur, Rishabh Anand Omar, Neetu Talreja, Divya Chauhan, Mohammad Ashfaq
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $2,500
OpenAlex ID: W4401800180