Work

Protocol to perform fragment screening using NMR spectroscopy

Year: 2024

Type: article

Abstract: N-heteronuclear single quantum coherence (HSQC) experiment, fragment deconvolution, determining binding affinities, and mapping the fragment-binding site. This protocol provides a strategy in fragment screening.

Source: STAR Protocols

DOI: 10.1016/j.xpro.2024.103278

Authors: Qiwei Huang, CongBao Kang

Institutions: Agency for Science, Technology and Research, Experimental Drug Development Centre

Language: English

Topic: Advanced NMR Techniques and Applications

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,500

OpenAlex ID: W4401815993

FWCI:

Cites: 16

Cited by:

Related to: 10