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Photosensitive Nanoprobes for Rapid High Purity Isolation and Size‐Specific Enrichment of Synthetic and Extracellular Vesicle Subpopulations (Adv. Funct. Mater. 34/2024)

Year: 2024

Type: article

Abstract: Photosensitive Nanoprobes In article number 2400390, Roshan W. Gunasekara, Sathish Ramakrishnan, and co-workers develop photosensitive lipid nanoprobes to isolate high-purity native extracellular vesicles while maintaining their nativity and functionality. Utilizing hydrophobic interactions and photochemistry, these probes separate vesicles into size-specific subpopulations. This unique property aids in understanding vesicle biogenesis, as size variability may indicate diverse cellular origins and functions, and facilitates the engineering of uniform vesicle populations.

Source: Advanced Functional Materials

DOI: 10.1002/adfm.202470191

Authors: Jonathan S. Weerakkody, Tiffany Tseng, Mackenzie Topper, Sikha Thoduvayil, Abhijith Radhakrishnan, Frederic Pincet, Themis R. Kyriakides, Roshan W. Gunasekara, Sathish Ramakrishnan

Institutions: Yale University, Centre National de la Recherche Scientifique, Université Paris Sciences et Lettres, École Normale Supérieure - PSL, Sorbonne Université, Laboratoire de Physique de l'Ecole Normale Supérieure

Language: English

Topic: Extracellular vesicles in disease

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

OpenAlex ID: W4401828274

FWCI: 0.116

Cites:

Cited by: 1

Related to: 10