Work

Neutrophils activated by micropatches hold promising prospects in tumor immunotherapy

Year: 2024

Type: article

Abstract: This study used polymer micropatches as a platform for sustained and targeted activation of neutrophils. The micropatches can promote the rapid conversion of neutrophils to the N1 type while also enhancing the activation of other immune cells in vivo. The activated neutrophils are recruited to the tumor site, where they exert effective antitumor effects.

Source: MedComm – Biomaterials and Applications

DOI: 10.1002/mba2.93

Authors: Mengran Chen, Bingyang Chu, Yu Wu

Institutions: Sichuan University, West China Hospital of Sichuan University, State Key Laboratory of Biotherapy

Language: English

Topic: Immune cells in cancer

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: National Natural Science Foundation of China, Sichuan Province Science and Technology Support Program