Work

Development of Inducible Packaging Cell Line for Raav Production Via Crispr-Cas9 Mediated Site-Specific Integration

Year: 2024

Type: article

Source: Biochemical Engineering Journal

DOI: 10.1016/j.bej.2024.109552

Authors: Qiang Fu, Yongdan Wang, Emily Doleh, Mark Blenner, Seongkyu Yoon

Institutions: University of Massachusetts Lowell, University of Delaware

Language: English

Topic: Virus-based gene therapy research

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Advanced Mammalian Biomanufacturing Innovation Center, National Science Foundation, Massachusetts Life Sciences Center, Korea Advanced Institute of Science and Technology, National Institutes of Health

Awards: IUCRC Phase II+: University of Massachusetts Lowell: Advanced Mammalian Biomanufacturing Innovation Center (AMBIC), Establishing a stable production cell line for recombinant AAV through synthetic dynamic regulation and reducing regulatory and metabolic limitations

OpenAlex ID: W4403987066

FWCI: 1.592

Cites: 48

Cited by: 6

Related to: 10