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Figure 4 from Characterizing Relationships between T-cell Inflammation and Outcomes in Patients with High-Risk Neuroblastoma According to Mesenchymal and Adrenergic Signatures

Year: 2024

Type: other

Abstract: MESadj and TCI scores are inversely correlated with features of high-risk neuroblastoma. MESadj and TCI are correlated in both the (A) Discovery and (B) Validation cohorts and inversely correlated with MYCN amplification, stage, and age in the Discovery cohort. Colored circle representing the correlation coefficient shown only for those correlations with P < 0.05. In the Discovery cohort, TCI and MESadj decrease with increasing stage (C and D), although 4S tumors have lower TCI and higher MESadj.

DOI: 10.1158/2767-9764.26861873.v1

Authors: Maria E. Kaufman, Omar R. Vayani, Kelley Moore, Alexandre Chlenski, Tong Wu, Sang Mee Lee, Ami V. Desai, Chuan He, Susan L. Cohn, Mark A. Applebaum

Language: English

Topic: Neuroblastoma Research and Treatments

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4401978326

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