Applications of CRISPR/CAS9 Technology in Mice and Livestock Genome Editing: Current Research
Year: 2024
Type: article
Abstract: Clustered regulatory interspaced short palindromic repeats/CRISPR-associated protein 9 (CRISPR/Cas9) technology is a novel and one of the most promising gene editing methods. Here we review the current research on the use of CRISPR/Cas9 technology to edit the genomes of mice, rabbits, pigs, sheep, goats, and cattle, as well as current obstacles and perspectives that may arise thanks to this technology. CRISPR/Cas9 has an advantage over other gene editing methods because of its simple design and the ease of modifying multiple target sites (multiplexing). This technology allows for the creation of in vitro and in vivo models of many diseases, which may contribute to the development of new drugs and effective therapies. CRISPR/Cas9 can also revolutionize the meat, dairy, leather, and fur industries by genetically modifying animals to obtain different products.
Source: Annals of Animal Science
Authors: Dorota Maj, Klaudiusz Górka
Institution: University of Agriculture in Krakow
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
SDG: Zero hunger
Open Access status: diamond
OpenAlex ID: W4401995361