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Advances in the Role and Mechanism of the 14-3-3 Protein Family in Hepatocellular Carcinoma

Year: 2024

Type: article

Abstract: The 14-3-3 protein family contains multiple isoforms that are expressed in different tissues and play key roles in cellular physiological functions through binding to related molecules. This article discusses in detail the role of 14-3-3 proteins in the progression of hepatocellular carcinoma, highlights their regulatory role in cell proliferation, migration, invasion, apoptosis, and autophagy, and emphasizes the potential of using 14-3-3 proteins as therapeutic targets in hepatocellular carcinoma. The article provides a comprehensive review of the role of the 14-3-3 protein family in hepatocellular carcinoma and its mechanisms.

Source: Journal of Contemporary Medical Practice

DOI: 10.53469/jcmp.2024.06(08).58

Authors: Xinya Wen, Kailin Jiao, Zhaoshuang Li, Yue Hao, Jin Zheng

Institutions: Shaanxi University of Chinese Medicine, Air Force Medical University

Language: English

Topic: 14-3-3 protein interactions

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4401997798

FWCI:

Cites: 36

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Related to: 10