Year: 2024
Type: article
Abstract: Novel Corona Virus Pneumonia (Corona Virus Disease 2019, COVID-19) in December 2019 became an epidemic disease. Chronic kidney disease (CKD) patients are highly sensitive to COVID-19, in-depth study and understanding of the mechanism of action and prevention and treatment strategies of CKD patients infected with novel coronavirus appears to be crucial. This article explored the selected topic by combing the relevant literature, and summarized the susceptibility to COVID-19 and the mechanism of renal involvement in CKD patients; the article shows that COVID-19 mainly enters the cells with ACE2 as the receptor to damage the kidneys directly, but also through cytokine storm, endothelial damage, immune dysregulation and other indirect ways of renal damage.
Authors: Xian Lu, Genping Lei, Dong Yang, Jingxue Bai
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4402000071