Work

Breast cancer and rectal cancer associated with Lynch syndrome: A case report

Year: 2024

Type: article

Abstract: BACKGROUND: The development mechanisms of Lynch syndrome (LS)-related breast cancer (BC) and rectal cancer are complex and variable, leading to personalized variations in diagnosis and treatment plans. CASE SUMMARY: This paper presents a comprehensive review of clinical diagnosis and treatment data from a patient with LS-associated BC and rectal cancer. Moreover, screening data and management guidelines, as well as relevant literature on LS, are included in this report. This study summarizes the molecular pathogenesis, clinicopathological features, and screening and management protocols for LS-associated BC and rectal cancer. CONCLUSION: Implementing early screening, prevention, and timely diagnosis and treatment measures is expected to reduce mitigate the incidence and mortality of LS-related BC and rectal cancer.

Source: World Journal of Clinical Oncology

DOI: 10.5306/wjco.v15.i9.1215

Authors: Pei-Fang Qin, Ling Yang, Jun-Ping Hu, Jing-Yue Zhang

Institution: Guigang City People's Hospital

Language: English

Topic: Genetic factors in colorectal cancer

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: Guangxi Medical University