Work

Ceftazidime-Avibactam Treatment for Carbapenemase-Producing Enterobacterales in a South African Children’s Hospital

Year: 2024

Type: article

Abstract: This study describes ceftazidime-avibactam use in 17 young children from a resource-constrained country, where intra-abdominal infection was common. All-cause mortality was 53%. Earlier initiation, dose optimization, recording infusion times, and reviewing the need for additional antibiotics were identified as easy-to-implement-antimicrobial-stewardship interventions.

Source: Journal of the Pediatric Infectious Diseases Society

DOI: 10.1093/jpids/piae087

Authors: Hafsah Deepa Tootla, Saamiya Van Niekerk, Thandolwethu Gumede, James Nuttall, Shamiel Salie, Brian Eley

Institutions: Red Cross War Memorial Children's Hospital, University of Cape Town

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4402038388