Synthesis of 2‐Amino Benzazoles Through Elemental Selenium‐Promoted Cyclization of Ortho ‐Substituted Anilines and Isocyanides
Year: 2024
Type: article
Abstract: A facile and transition metal‐free method has been developed for the synthesis of 2‐amino benzazoles through elemental selenium promoted cyclization reaction of ortho ‐substituted anilines with isocyanides under mild conditions. Through this strategy, a series of 2‐amino benzooxa/(thia)zoles and benzimidazoles could be efficiently obtained in good to excellent yields with favorable functional group tolerance.
Authors: Hongyu Ding, Chao Ma, Siyu Shi, Wenxiu Cui, Yufen Lv, Jinmao You, Wei Wei, Dong Yi
Language: English
Subfield: Toxicology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W4402076659