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Paroxysmal nocturnal hemoglobinuria presenting as acute renal injury

Year: 2024

Type: article

Abstract: Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired chronic hemolytic anemia characterized by persistent intravascular hemolysiswith occasional or frequent recurrent exacerbations. In addition to hemolysis, there may be, pancytopenia and a distinct tendency to venous thrombosis. This triad makes PNH a truly unique clinical condition; however, not all of these three features manifest on presentation. Not many reports of renal involvement in PNH are available in the literature. We report a case of acute kidney injury (AKI) due to PNH. This case shows AKI as one of the complications of PNH.

Source: International Journal of Research in Medical Sciences

DOI: 10.18203/2320-6012.ijrms20242632

Authors: Sandeep Saini, Himadri Koley, Dipesh K. Dhoot, Chandrashekar Cheluvaiah, Rohit Puri, Devada S. Karunanidhi, Basavaraj Jatteppanavar, Anshuman Biswal, Parul Ahlawat

Institution: All India Institute of Medical Sciences Rishikesh

Language: English

Topic: Complement system in diseases

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4402080668

FWCI:

Cites: 10

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Related to: 10