Work

Giant Dermatofibrosarcoma Protuberans Originating from a Keloid Scar-A Case Report and Review

Year: 2024

Type: article

Abstract: Dermatofibrosarcoma protuberans (DFSP) is a rare cutaneous sarcoma derived from dermal fibroblasts and accounts for 1-6% of all cutaneous soft tissue sarcomas.These low-grade tumors typically follow an indolent early course marked by slow growth but have a small potential to exhibit rapid growth with high-grade transformation.DFSPs are clinically similar to benign fibro proliferative skin tumors such as keloids, which may lead to misdiagnosis and delays in treatment.We present a case of DFSP originating from a keloid scar on the right breast.Here, we highlight the difficulty of timely diagnosis and need for multidisciplinary care.Excision of large tumors often leave significant defects requiring local tissue rearrangements, skin grafts, or complex reconstruction.Further, we review pertinent literature and outline the nuanced challenges of DFSP management.

Source: Annals of Case Reports

DOI: 10.29011/2574-7754.101930

Authors: Andrew A Francis, Megan Newsom, Justin Chang, Steven Smith, Paschalia M Mountziaris, Timothy Harris, Harry D Bear

Institutions: Virginia Commonwealth University, VCU Massey Comprehensive Cancer Center, Virginia Commonwealth University Medical Center

Language: English

Topic: Soft tissue tumor case studies

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4402093255