Work

Muc16CD is a novel CAR T cell target antigen for the treatment of pancreatic cancer

Year: 2024

Type: article

Abstract: with significantly enhanced tumor control and survival benefits in a pancreatic tumor model. Overall, these findings demonstrate the utility of Muc16CD-targeted CAR T cell therapy in the novel setting of pancreatic cancer.

Source: Molecular Therapy Oncology

DOI: 10.1016/j.omton.2024.200868

Authors: Heather K. Lin, Dejah A. Blake, Tongrui Liu, Ruby Freeman, Gregory B. Lesinski, Lily Yang, Sarwish Rafiq

Institutions: Emory University, Winship Cancer Institute

Language: English

Topic: CAR-T cell therapy research

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,900

Funders: Mary Kay Foundation, Emory University, Georgia Clinical and Translational Science Alliance, Winship Cancer Institute, National Cancer Institute, National Institute of General Medical Sciences, ASH Foundation

Awards: Tumor Stroma Breaking System for Efficient Delivery of Therapeutic Agents, G5843540266, Stroma penetrating and immune modulating nanoparticles for image-guided therapy of pancreatic cancer

OpenAlex ID: W4402125768

FWCI: 1.676

Cites: 52

Cited by: 11

Related to: 10