Work

Studies on Propranolol hydrochloride floating tablets formulated with different concentrations of Aegle marmelos gum

Year: 2024

Type: article

Abstract: This research employs Aegle marmelos gum in various ratios as a natural polymer to formulate and assess Propranolol hydrochloride floating tablets. Because of its high solubility and permeability, propranolol hydrochloride, a non-selective beta-adrenergic receptor blocker, has a restricted bioavailability. Floating tablets are intended to improve the absorption and bioavailability of drugs by staying afloat in the stomach. Aegle marmelos gum (AMG) was used as a polymer in varied ratios to create distinct formulations. The tablets were then tested for a number of characteristics, including hardness, friability, drug content, in vitro buoyancy, and drug release profiles. The findings showed that the Aegle marmelos gum content had a major impact on the tablets' floating qualities and drug release characteristics.

Source: Journal of Advances in Science and Technology

DOI: 10.29070/f97k6921

Authors: Dr. Eman Nazmi Al Qutub Dr. Eman Nazmi Al Qutub, Dr. Khoulod Nazmi Al Qutub Dr. Khoulod Nazmi Al Qutub, Dr. Dr. Manal Nazmi Al Qutub Dr. Dr. Manal Nazmi Al Qutub

Institution: Princess Nourah bint Abdulrahman University

Language: English

Topic: Advanced Drug Delivery Systems

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4402138144

FWCI:

Cites: 13

Cited by:

Related to: 10