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Unraveling the neurological intricacies: a rare case of Guillain-Barre syndrome in dengue fever

Year: 2024

Type: article

Abstract: Dengue, caused by the dengue virus, presents with various clinical manifestations, including rare neurological complications. Guillain-Barre Syndrome (GBS), an immune-mediated polyradiculoneuropathy, is a rare complication, often triggered by antecedent infections. Herein, we report the case of a 30-year-old male presenting with GBS following dengue fever. His clinical course revealed classic GBS symptoms, including ascending weakness and bulbar involvement, with no noted infection that could plausibly explain a trigger for GBS. Diagnosis entailed cerebrospinal fluid analysis and nerve conduction studies which confirmed acute inflammatory demyelinating polyradiculoneuropathy. Treatment involved plasmapheresis, yielding a positive response. This case underscores the association between dengue and GBS, emphasizing the need for heightened clinical suspicion in endemic regions like Nepal.

Source: Oxford Medical Case Reports

DOI: 10.1093/omcr/omae099

Authors: Aadesh Rayamajhi, Sandesh Rayamajhi, Saurav Agrawal, Niraj Gautam

Institutions: Tribhuvan University, Maharajgunj Medical Campus, Institute of Medicine, Nepalese Army Institute of Health Services, Tribhuvan University Teaching Hospital

Language: English

Topic: Peripheral Neuropathies and Disorders

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,180