The Paradox of Modern Technology in Standardizing Thermal Liver Ablation: Fostering Uniformity or Diversity?
Year: 2024
Type: article
Study design: Observational Study
Abstract: PURPOSE: Currently, significant medical practice variation exists in thermal ablation (TA) of malignant liver tumors with associated differences in outcomes. The IMaging and Advanced Guidance for workflow optimization in Interventional Oncology (IMAGIO) consortium aims to integrate interventional oncology into the standard clinical pathway for cancer treatment in Europe by 2030, by development of a standardized low-complex-high-precision workflow for TA of malignant liver tumors. This study was conducted at the start of the IMAGIO project with the aim to explore the current state and future role of modern technology in TA of malignant liver tumors. MATERIALS AND METHODS: A cross-sectional questionnaire was conducted followed by an expert focus group discussion with core members and collaborating partners of the consortium. RESULTS: Of the 13 participants, 10 respondents filled in the questionnaire. During the focus group discussion, there was consensus on the need for international standardization in TA and several aspects of the procedure, such as planning based on cross-sectional images, the adoption of different techniques for needle placement and the importance of needle position- and post-ablative margin confirmation scans. Yet, also considerable heterogeneity was reported in the adoption of modern technology, particularly in navigational systems and computer-assisted margin assessment. CONCLUSION: This study mirrored the current diversity in workflow of thermal liver ablation. To obtain comparable outcomes worldwide, standardization is needed. While advancements in tools and software hold the potential to homogenize outcome measurement and minimize operator-dependent variability, the rapid increase in availability also contributes to enhanced workflow variation.
Authors: Coosje A. M. Verhagen, Ariadne L. van der Velden, Reto Bale, Elena Bozzi, Laura Crocetti, Alban Denys, Gonnie C. M. van Erp, Faeze Gholamiankhah, Giorgio Greco, Pim Hendriks, Robrecht R. M. M. Knapen, Hicham Kobeiter, Rodolfo Lanocita, Martijn R. Meijerink, Franco Orsi, Alice Phillips, Hossein Rahmani, Maarten L. J. Smits, Marco J. L. van Strijen, Ronald M. van Dam, Christiaan van der Leij, Mark C. Burgmans
Institutions: Leiden University Medical Center, Maastricht University Medical Centre, Maastricht University, Innsbruck Medical University, Universität Innsbruck, Azienda Ospedaliera Universitaria Pisana, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Fondazione IRCCS Istituto Nazionale dei Tumori, Université Paris-Est Créteil, Assistance Publique – Hôpitaux de Paris, Hôpitaux Universitaires Henri-Mondor, Amsterdam UMC Location University of Amsterdam, Amsterdam University Medical Centers, European Institute of Oncology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University Medical Center Utrecht, St. Antonius Ziekenhuis
Language: English
Subfield: Hepatology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $4,190
OpenAlex ID: W4402170726
