Work

A Cyclometalated Iridium(III) Complex Exerts High Anticancer Efficacy via Fatty Acid Beta-Oxidation Inhibition and Sphingolipid Metabolism Reprogramming

Year: 2024

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.4c00280

Authors: Cuiyan Lin, Huiling Wang, Keyu Chen, Shuangqiang Liu, Zhichen Mao, Zuyu Mo, Rizhen Huang, Ye Zhang, Wei Xie, Jianhua Wei, Junfei Jin

Institutions: Guilin Medical University, Guangxi Normal University, State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, Southeast University, Affiliated Hospital of Guilin Medical College

Language: English

Topic: Cancer, Lipids, and Metabolism

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Natural Science Foundation of Guangxi Zhuang Autonomous Region, National Natural Science Foundation of China, Science and Technology Department of Guangxi Zhuang Autonomous, Guilin Medical University, Guilin Science and Technology Bureau, State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources

Awards: G2599398841, G3024271349, G5389177808, G7263213759, G7826412289, G8719074041, G8997379716

OpenAlex ID: W4402187190

FWCI: 0.931

Cites: 64

Cited by: 6

Related to: 10