Work

Novel Celecoxib Derivative, RF26, Blocks Colon Cancer Cell Growth by Inhibiting PDE5, Activating cGMP/PKG Signaling, and Suppressing β-catenin-dependent Transcription

Year: 2024

Type: article

Source: Anti-Cancer Agents in Medicinal Chemistry

DOI: 10.2174/0118715206318802240821114353

Authors: Sara Sigler, Mohammad Abdel-Halim, Reem K. Fathalla, Luciana Madeira Da Silva, Adam B. Keeton, Yulia Y. Maxuitenko, Kristy L. Berry, Gang Zhou, Matthias Engel, Ashraf H. Abadi, Gary A. Piazza, Gary A. Piazza

Institutions: USA Mitchell Cancer Institute, University of South Alabama, German University in Cairo, Auburn University, Augusta University, Saarland University

Language: English

Topic: Phosphodiesterase function and regulation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Institutes of Health, National Cancer Institute

Awards: Development of a novel sulindac amide for colorectal cancer chemoprevention, G3881944549, Phosphodiesterase 10A, a novel target for lung cancer chemoprevention, Phosphodiesterase 5: A Novel Target and Inhibitor for Breast Cancer Chemopreventi, G9000122409, G9000298641

OpenAlex ID: W4402192281

FWCI: 0.346

Cites: 46

Cited by: 3

Related to: 10