Frequency of Renal Impairment Among Patients with Liver Cirrhosis with Spontaneous Bacterial Peritonitis
Year: 2024
Type: article
Study design: Observational Study
Abstract: Objective: This study aim was to ascertain the prevalence of renal impairment among patients diagnosed with spontaneous bacterial peritonitis resulting from liver cirrhosis. Methods: The descriptive cross-sectional study was conducted in the Department of Gastroenterology, Hayatabad Medical Complex, located in Peshawar. The study duration was 6 months from September 29th, 2022 to March 29th, 2022. A cohort of 212 individuals was examined to ascertain the prevalence of renal dysfunction among patients afflected with spontaneous bacterial peritonitis because of liver cirrhosis. Results: A total of 212 patients were recruited in which 34.3% (n=72 ) were found in aged 31-40 years. The mean age of the participants was 51.5±3.3 years. Among total, 87 (41.4%) were male and 123 (58.6%) were female patients. Among total, 48 (22.9%) were found in underweight range. It was observed that 96 patients (45.7%) had renal impairment, while 114 patients (54.3%) not affected with renal impairment. The analysis revealed that smoking was seen in 80 individuals (38.1%), whereas hypertension was observed in 120 individuals (57.1%). Conclusion: Renal impairment has significant prevalent occurrence among cirrhotic patients presenting with ascites and spontaneous bacterial peritonitis (SBP). The SBP-RI variable has significant predictive value for hospital mortality in individuals diagnosed with SBP. Individuals who have significantly compromised liver function or pre-existing kidney failure are more susceptible to the development of spontaneous bacterial peritonitis with renal impairment.
Authors: Muhammad Hanif Hadi, Muhammad Aasim Khan, Muhammad Javeed, Arshad Khan, Asif Nawaz
Institution: Gajju Khan Medical College
Language: English
Subfield: Hepatology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4402196156