Work

Identification of a histone deacetylase inhibitor as a therapeutic candidate for congenital central hypoventilation syndrome

Year: 2024

Type: article

Abstract: . Thus, our results identify SAHA as a promising agent to treat CCHS-associated breathing deficiencies.

Source: Molecular Therapy — Nucleic Acids

DOI: 10.1016/j.omtn.2024.102319

Authors: Chiara Africano, Tiziana Bachetti, Paolo Uva, Gabriel Pitollat, Genny Del Zotto, Francesca Giacopelli, Giada Recchi, Nicolas Lenfant, Amélia Madani, Nathan Beckouche, Muriel Thoby-Brisson, Isabella Ceccherini

Institutions: Istituto Giannina Gaslini, University of Genoa, Ospedale Policlinico San Martino, Centre National de la Recherche Scientifique, Université de Bordeaux, Institut de Neurosciences Cognitives et Intégratives d’Aquitaine, Inserm, Aix-Marseille Université, Université Paris Cité, NeuroDiderot

Language: English

Topic: Neuroscience of respiration and sleep

Subfield: Endocrine and Autonomic Systems

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,900

Funder: Ministero della Salute

Award: G249627624

OpenAlex ID: W4402197802

FWCI: 1.007

Cites: 66

Cited by: 6

Related to: 10