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A Case of Hyponatremic Hypertensive Syndrome With Neurologic Sequelae Secondary to Unilateral Renal Artery Stenosis

Year: 2024

Type: article

Abstract: In cases of unilateral renal artery stenosis, acute exacerbations may present as hyponatremic hypertensive syndrome (HHS), a rare and highly morbid complication. Its insidious onset, low incidence, and often counter-intuitive laboratory profile can delay diagnosis and worsen outcomes. Furthermore, complications including end-organ ischemia, polyelectrolyte derangement, and hypertensive crises can occur. Herein, we present a 62-year-old man with known right renal artery stenosis who presented with HHS in hypertensive emergency with encephalopathy. Consideration of the underlying pathomechanism and careful fluid and electrolyte repletion can minimize complications and improve clinical outcomes in this highly morbid and precarious clinical syndrome.

Source: Cureus

DOI: 10.7759/cureus.68544

Authors: Carson Clark, Kai Yoshinaga, Artem Tkachenko, Thomas Murphy

Institutions: Wright State University, Dayton VA Medical Center

Language: English

Topic: Electrolyte and hormonal disorders

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4402199688