Work

Effects of Perioperative Fluid Management on Endothelial Glycocalyx in Radical Cystectomy: A Randomized Clinical Trial

Year: 2024

Type: article

Abstract: What's known on the subject? and What does the study add?Major abdominal surgeries are known to cause large amounts of fluid shifts in vivo, occasionally depending on the fluid therapy modality.Theoretically, excessive fluid replacement leads to glycocalyx damage; however, it is not well established how to follow-up such damage and its clinical implications.In this study, biochemical degradation products of glycocalyx and their relationship with liberal fluid therapy are demonstrated, although there may not be any clear change in hemodynamic monitoring.

Source: Journal of Urological Surgery

DOI: 10.4274/jus.galenos.2024.2024-2-1