Work

Discontinuous hyperpolarization schemes in liquid-state overhauser dynamic nuclear polarization experiments

Year: 2024

Type: article

Abstract: Liquid-state Overhauser Dynamic Nuclear Polarization (ODNP) is an emerging technique, aimed at shortening NMR experiment times. It achieves this by increasing the otherwise poor nuclear polarization at room temperature, by polarization transfer from excited electron spins. The present work explores two ideas, aimed at achieving the optimal signal-to-noise per time unit for a given system, and quantitation of spectra showing a large disparity in ODNP enhancements at high magnetic fields (≥ 9.4 T). Both of these ideas are predicated on, perhaps counterintuitively, not allowing full dynamic nuclear polarization to build up, either by rapid rf pulsing, or gating of the microwave irradiation.

Source: Journal of Magnetic Resonance Open

DOI: 10.1016/j.jmro.2024.100160

Author: Alex van der Ham

Language: English

Topic: Advanced NMR Techniques and Applications

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,500

Funders: Max-Planck-Gesellschaft, European Research Council, H2020 European Research Council

Award: New routes for magnetic resonance spectroscopy of biomolecules by combining EPR and NMR methods