Aerosolic Application of Phages Against S. infantis on Plates and Chicken Skin
Year: 2024
Type: article
Abstract: Phages are known as a promising method to combat antimicrobial resistance (AMR) in the human and veterinary sector. Use of phage aerosols enormously increases the application field, although the impact on the infectivity of phages during nebulization needs to be evaluated. In this study S. infantis was treated on plates and chicken skin with nebulized phage particles of the Myoviridae type, identified by transmission electron microscopy, using a commercial nebulizer primarily used for H 2 O 2 disinfection. The reduction of bacterial number by aerosol applied phage particles was evaluated. It could clearly be shown that the phage particles were able to infect Salmonella after being nebulized using ultrasound technology. Further studies on other types of phages as well as other conditions must be performed to standardize the aerosolic application of phages.
Source: PHAGE
Authors: Lisa Winkelmayer, Krista Rathammer, Susanne Richter, Theres Requat, Monika Matt, Davul Ljuhar, Philippe Jäger, Friedrich Kernmauner, Seyed Naemi, Michael Dieter Mansfeld, Georg G. Duscher
Institution: Austrian Agency for Health and Food Safety
Language: English
Subfield: Ecology
Field: Environmental Science
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4402237535