Development and characterization of a zeolite based drug delivery system: Application to cannabidiol oral delivery
Year: 2024
Type: article
Abstract: adsorption analysis indicated that CBD was successfully loaded into the zeolite matrix. When compared to CBD containing particles in a commercialized capsule, the in-vitro dissolution rate of CBD loaded zeolite was significantly higher after 30 min in the simulated stomach (pH 1.8) and the intestinal (pH 6.8) fluids, 67.8 % versus 43.6 % and 62.6 % vs 38.4 % respectively. Our findings open new avenues for the use of zeolites as an efficient drug delivery system for drugs with low bioavailability like CBD.
Source: Heliyon
Authors: Fouad Dernaika, Layal Halawy, Joseph Zeaiter, Sara Kawrani, Dima Mroue, Anthony Lteif, Sima Kourani, Mohamed Mehanna, Celine Abboud, Mohamad Mroueh, Aline Milane
Institutions: Lebanese American University, American University of Beirut
Language: English
Subfield: Pharmaceutical Science
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $2,100
Funder: Lebanese American University
OpenAlex ID: W4402252140