Work

Prognostic factors of postoperative morbidity in surgery for resectable pancreatic cancer. Regional institute of neoplastic diseases ‘Dr. Luis Pinillos Ganoza’ IREN Norte. 2007–2022

Year: 2024

Type: article

Abstract: Ganoza' -IREN Norte.2007-2022. Materials and methods:A study was conducted with a case-based (22 patients) and control (14 patients) design nested in a cohort that included 36 patients who underwent proximal duodenopancreatectomy (Whipple) or distal pancreatectomy for pancreatic cancer.Results: In the present study, it was found that the total number of living patients represents 86.1% of the total (36 patients).Of the total population, patients who presented only 1 complication were 13.6% and more than 1 complication were 86.4%.It was also found that the most frequent complication in the general population was gastric emptying syndrome, which was present in 50% of all patients.In the bivariate analysis, a highly significant association was observed between the low prognostic nutritional index (p < 0.001, OD = 20.400,CI = 95%: (3.377-123.245)),the type of pancreatic resection (p < 0.001, OR = 52.500,CI = 95%: (5.174-532.669))and postoperative morbidity.In contrast, no significant association was found between age ≥65 (p = 0.062), diabetes mellitus (p < 0.908), Wirsung diameter (p < 0.432), hospital stay (p < 0.075) and postoperative morbidity.In the multivariate analysis, serum total bilirubin level ≥20 μmol/L (p = 0.778), use of preoperative biliary drainage (p = 0.176), type of pancreatojejunal anastomosis (p = 0.533) and pancreaticogastric anastomosis (p = 0.504) were not statistically significantly associated with postoperative morbidity. Conclusion:The type of pancreatic resection and the nutritional prognostic index <40.5 are prognostic factors of postoperative morbidity in postoperative patients for resectable pancreatic cancer.

Source: ecancermedicalscience

DOI: 10.3332/ecancer.2024.1754

Authors: Aldaír Guzmán-Aponte, Juan Alberto Díaz-Plasencia, Edgar Fermín Yan-Quiroz, José Richard Tenazoa-Villalobos

Institutions: Antenor Orrego Private University, EsSALUD

Language: English

Topic: Pancreatic and Hepatic Oncology Research

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,226