Work

Evaluation of Glycosylation Patterns and Inhibition in Acute Lymphoid Leukemia

Year: 2024

Type: article

Abstract: Objective: Acute lymphoblastic leukemia (ALL) is a heterogeneous hematologic disease characterized by the proliferation of immature lymphoid cells in the bone marrow, peripheral blood, and other organs. O-linked glycosylation patterns on lymphoid cells are common modifications located on the hydroxyl groups of serine or threonine residues. Glycosylation patterns are associated with key functions including cellular uptake, regulation, and signaling of immune cells, as well as adhesion and migration.

Source: American Journal of Pharmaceutical Education

DOI: 10.1016/j.ajpe.2024.101214

Authors: Kenny Pham, Daniel Muteba, Ghada Alhafez, Robert Campbell

Institution: Massachusetts College of Pharmacy and Health Sciences

Language: English

Topic: Glycosylation and Glycoproteins Research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,400