Phenolic Compound Profiles, Antioxidant, and Cytoprotective Activity of Elaeagnus conferta Roxb. Fruit
Year: 2024
Type: article
Abstract: In this paper, three varieties of Elaeagnus conferta Roxb fruits prepared by ultrasonic‐assisted extraction from a subtropical region southwest of China were utilized as raw materials to investigate their phenolic profiles, antioxidant activities, and protective effects on injured human umbilical vein endothelial cells (HUVECs). The ultra performance liquid chromatography‐electrospray ionization tandem mass spectrometry (UPLC‐ESI‐MS/MS) findings revealed that fifteen substances, including seven phenolic acids, seven flavonoids, and one gallic acid derivative, were discovered. The dihydromyricetin, ellagic acid, gallic acid were the predominant phenolic compounds in all E.conferta fruits. These E.conferta fruits extracts shown excellent antioxidant activity varied from 2.258±0.03~7.844±0.39 μM Trolox/g and protective effect on HUVECs injured by H2O2 through decrease the level of ROS, MDA, LDH and enhance the SOD level. These finding indicate that E.conferta is a valuable source of high‐capacity antioxidants that might be used as an alternative material for food industries.
Source: Chemistry & Biodiversity
Authors: Jun Lu, Dingli Liu, Jing Cheng, Shende Hu, Zhengyu Yang, Lin Zhang, Jiali Ren
Institution: Central South University of Forestry and Technology
Language: English
Subfield: Biochemistry
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4402270027