Work

Defunctionalization Enabled by Intramolecular Radical Aromatic Ipso Substitution

Year: 2024

Type: article

Abstract: A chemoselective and regioselective copper-promoted defunctionalization procedure has been developed, enabling the rapid construction of various N -polyheterocycles. Initial mechanistic studies reveal that a single-electron transfer radical process is potentially involved.

Source: Organic Letters

DOI: 10.1021/acs.orglett.4c02910

Authors: Qijing Zhang, Tinglan Liu, Lili Wu, Cong-Ying Zhou, Chengming Wang

Institution: Jinan University

Language: English

Topic: Radical Photochemical Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: Central University Basic Research Fund of China, Basic and Applied Basic Research Foundation of Guangdong Province

Awards: G4239131767, G6073123326, G7122649276