Work

Enhancing Neurosteroidogenesis Attenuates HIV-1 Tat Mediated Stress-Related Outcomes

Year: 2024

Type: article

Abstract: Objective: To investigate the potential role of the neurotoxic HIV-1 regulatory protein, trans-activator of transcription (Tat), in hypothalamic-pituitary-adrenal (HPA) axis dysfunction and associated affective disorders, and to explore the hypothesis that enhancing neurosteroidogenesis could ameliorate Tat-mediated HPA dysfunction.

Source: American Journal of Pharmaceutical Education

DOI: 10.1016/j.ajpe.2024.100823

Authors: Salahuddin Mohammed, Fakhri Mahdi, Jason Paris

Institutions: Notre Dame of Maryland University, University of Mississippi

Language: English

Topic: Stress Responses and Cortisol

Subfield: Behavioral Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,400