Work

Novel Dual PPAR δ/γ Partial Agonist Induces Hepatic Lipid Accumulation through Direct Binding and Inhibition of AKT1 Phosphorylation, Mediating CD36 Upregulation

Year: 2024

Type: article

Source: Chemical Research in Toxicology

DOI: 10.1021/acs.chemrestox.4c00268

Authors: Xiaotong Cai, Qin Zhang, Jiwei Wang, Yingying Miao, Yuqing Sun, Ziyin Xia, Luyong Zhang, Qinwei Yu, Zhenzhou Jiang

Institutions: China Pharmaceutical University, State Key Laboratory of Natural Medicine, Guangdong Pharmaceutical University

Language: English

Topic: Peroxisome Proliferator-Activated Receptors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, China Postdoctoral Science Foundation, Natural Science Foundation of Jiangsu Province

Awards: G1879102125, G5855658470, G6316985103, G722473083

OpenAlex ID: W4402272980

FWCI: 0.471

Cites: 38

Cited by: 4

Related to: 10