Complete laparoscopic management of locally recurrent renal cell carcinoma after radical nephrectomy
Year: 2024
Type: article
Study design: Observational Study
Abstract: Objective: Description of the laparoscopic approach for local recurrence of renal cell carcinoma after radical nephrectomy and oncological outcomes. Study design: A retrospective cohort analysis. Materials and methods: A retrospective cohort analysis included patients who underwent laparoscopic resection for RCC recurrence at XXX. The laparoscopic technique utilized either transabdominal or retroperitoneal approaches. The primary outcome measure was disease-free survival. Secondary outcome measures included operative time, estimated blood loss, and complications. Results: Thirteen patients underwent laparoscopic resection, with a mean operative time of 189 minutes and low complication rates. Pathological reports confirmed clear-cell RCC in the majority of cases. The median time to recurrence post-nephrectomy was 67 months, with a 3-year disease-free survival rate of 85%. All patients had negative margins, and at the last follow-up all patients were alive. Limitations: The limitations of this study include its small sample size and retrospective design. Value: The full laparoscopic approach for patients with local recurrence of renal cell carcinoma. Conclusion: Laparoscopic resection of locally recurrent RCC post-radical nephrectomy appears to be safe and effective, demonstrating promising oncological outcomes. Larger prospective studies are warranted to validate these findings and establish standardized guidelines for widespread implementation.
Source: Revista Mexicana de Urología
DOI: 10.48193/4s2h3424
Authors: Gastón Alejandro Fernández Candia, Juan Camean, Jorge Jaunarena, Joaquin Chemi, Roberto Villalba Bachur, Gustavo Villoldo
Institution: Instituto Alexander Fleming
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4402285823