Evaluation of Echocardiographic Parameters for Left Ventricle Systolic and Diastolic Dysfunctioni in Patients with Liver Cirrhosis
Year: 2024
Type: article
Study design: Observational Study
Abstract: Prevalence of cirrhotic cardiomyopathy is an issue hard to estimate, both nationally and worldwide. This clinical research sets out a more precise evaluation of systolic and diastolic functions in cirrhotic patients using proved parameters - the TEI Index- to estimate systolic and diastolic dysfunction and the E/Vp ratio for diastolic dysfunction. These parameters were compared with classic parameters typically employed. Study population was represented by 70 patients diagnosed with liver cirrhosis.Results showed increased sensitivity of the TEI Index - in detecting systolic dysfunction in cirrhotic patients, with an increased accuracy compared to left ventricular ejection fraction. Regarding the parameters for diastolic dysfunction, it was proved that E/Vp ratio, had an increased specificity in detecting diastolic dysfunction due to cirrhotic cardiomyopathy. In conclusion, the hypothesis that patients with liver cirrhosis could benefit from an improvement of diagnostic sensitivity of cirrhotic cardiomyopathy using the two suggested parameters was confirmed in our study. And more important, a significant positive correlation between the severity of diastolic dysfunction and the severity of liver disease was found.
Authors: D. Lupu, E.G. Condrea, C. Stanescu, A. Stoica, L. Nedelcu
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4402287344