Fabrication of nanogels to improve the toxicity and persistence of cycloxaprid against Diaphorina citri, the vector of citrus huanglongbing
Year: 2024
Type: article
Abstract: • A sustained-release nano-gelation particle was fabricated. • Cycloxaprid-loaded nano-gelation particles (Cyc@NGs) showed higher toxicity than Cyc in controlling Diaphorina citri. • Cycloxaprid-loaded nano-gelation particles (Cyc@NGs) protected Cyc from photolysis and rain wash. • Cyc@NGs possessed better wettability on citrus leaves, benefitting from its lower contact angle. • Nano-gelation particles (NGs) showed higher capability to penetrate and enrich in citrus leaf tissue and D. citri midgut. Diaphorina citri is the most serious pest of citrus worldwide because it is the natural insect vector of huanglongbing. Cycloxaprid (Cyc) was highly toxic to D. citri . However, the poor solubility and stability had limited its development. In order to improve the insecticidal effect and stability to harsh climatic conditions of Cyc. Cyc was chosen as the representative pesticide, 4,4′-methylenebis (phenyl isocyanate), PEG-600 and n-butanol were used to prepare sustained-release nano-gelation particles (Cyc@NGs). Cyc@NGs enhance the toxicity of Cyc more than 3 folds. Furthermore, Cyc@NGs showed excellent anti-rain and anti-UV capacity. After being exposed to ultraviolet light for 12 h, Cyc decreased by 100 %, while the insecticide content of Cyc@NGs only decreased by 25 %. Additionally, Cyc@NGs possessed better wettability on citrus leaves, mainly benefitting from its lower contact angle on citrus leaves. Moreover, FITC-labeled nano-gelation particles (FITC-NGs) exhibited high capability to penetrate and enrich in citrus leaf tissue and D. citri midgut. Consequently, NGs promoted the translocation and durability of insecticides, thereby, increasing the insecticidal activity. The results suggested that nano-gelation particle is a promising platform to deliver insecticides and Cyc@NGs would be the suitable candidate for the effective management of D. citri .
Source: Journal of Advanced Research
Authors: Li Cui, Guiyun Deng, Jianghong Wu, Fang Ding, Wenjie Wang, Haiyang Yu, Zhiyong Song, Changhui Rui, Heyou Han, Huizhu Yuan
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $3,000
Funders: Chinese Academy of Agricultural Sciences, Huazhong Agricultural University, National Key Research and Development Program of China, Agricultural Science and Technology Innovation Program, Central Public-interest Scientific Institution Basal Research Fund, Chinese Academy of Fishery Sciences
OpenAlex ID: W4402290167